The NanoVerita™ instrument lab-on-a-chip system is designed to deliver a sample-to-answer workflow for isolation and fluorescent imaging of macromolecular targets (e.g. cell-free DNA).
The NanoVerita™ system is built upon the same novel ACE platform that powers Biological Dynamics’ clinical diagnostic program and consists of an automated benchtop instrument and 8 channel consumable cartridge. The system interacts with nanoparticles via an ACE interface that allows for direct isolation of nanoparticles (diameter of ~40-500 nm) without the need to dilute physiological samples, such as plasma or serum.
The ExoVerita™ instrument is a flexible lab-on-a-chip system designed to support development of assays based on exosomes, cfDNA, and other extracellular vesicles. The ExoVerita™ system is also built upon the ACE platform and uses an ACE chip to reversibly capture macromolecules in biofluids, such as whole blood, serum, and plasma, enabling both on-chip detection of targets and downstream analysis, such as sequencing and PCR.
As part of our Early Technology Access Program, the system is available to select academic partners to develop the next generation of highly accurate diagnostic solutions.
ExoVerita™ System - Capabilities
The ExoVerita™ system enables a simplified, no-dilution workflow for the development of exosome-based assays, bypassing many fundamental limitations of current isolation technologies.
The video demonstrates capture of hmw cfDNA in undiluted whole blood. Input: whole blood, 17uL, gDNA spike The brightfield video demonstrates the separation of blood cells from nanoparticles; the FITC channel video shows the visualization of fluorescently tagged cfDNA.