Company & Leadership

The leadership team brings together considerable experience to the helm of Biological Dynamics, having demonstrated success in developing novel technology and building successful organizations at the front line of medical technology. From diverse cultural backgrounds and specializations, the team shares vision, passion for patient care, a focus on cutting-edge technology, and a deep commitment to innovation, which shapes the future of our company and drives our innovative culture.

About Our Company

Biological Dynamics is a private molecular diagnostics company located in San Diego. Founded in 2008, based on innovation developed at UC San Diego’s Jacobs School of Engineering, the company is pursuing the use of ACE technology to improve the challenging therapeutic decision-making processes involved in the treatment and monitoring of cancer, transplant, and traumatic brain injury patients.  Biological Dynamics first product, the TR(ACE)™ assay, will utilize the platform to support treatment response in oncology.

Since 2010, the company has successfully deployed 3 rounds of funding (>$30M in total), is starting clinical trials in 2016 for its first product - the TR(ACE)™ assay for oncology- and is carrying on work for its early non-oncology programs.

Raj Krishnan, PhD - CEO

Dr. Raj Krishnan founded Biological Dynamics in 2008 with the mission to revolutionize the approach toward the diagnosis and treatment of high burden diseases- the manifestation of his long desire to help people with cancer and save lives. Receiving his Ph.D. in Bioengineering from UC San Diego, Raj moved to build a company based on the technology he developed for his dissertation, where he pioneered the use of AC Electrokinetics for the purpose of blood-based diagnosis.

For the last several years, under Raj's vision and guidance, Biological Dynamics has transformed from concept to early stage startup, and then to one of the most innovative diagnostic companies in Southern California. His passion and conviction has led Biological Dynamics through 3 rounds of funding, securing over 30M in total. Raj has published several papers on AC Electrokinetics and was recently named to the Top 30 under 30 scientists by Forbes magazine.

Juan Pablo Hinestrosa, PhD - VP of R&D

JP joined the Biological Dynamics team in March 2013, after completing his PhD work in biomimetic systems and stimuli-responsive materials at Oak Ridge National Laboratory and the École Polytechnique Fédérale de Lausanne.  As the VP of R&D and BioDyn's core polymer scientist, JP leads the ACE chip technology performance optimization efforts, and ensures the company's technological readiness for commercial manufacturing.


Mark Adler, MD - Strategic Advisor

Dr. Adler's key role is a Strategic Advisor to the CEO. As a board-certified oncologist and Internist with a background in building and oversight of public companies, he supports Biological Dynamics leadership team with a blend of industry, corporate, and strategic perspectives.

Dr. Adler is Director of Genomic Oncology at the San Diego Cancer Research Institute and a member of WebMD Board of Directors. He is a founder of the San Diego Cancer Center (now UC San Diego Cancer Center), where he served as CEO and Medical Director for over 20 years. After Center's acquisition in 2011, Dr. Adler continued on as its Strategic Director until February, 2014. He continues his involvement in clinical trials and is now co-investigator with the J. Craig Venter Institute (JCVI) for its flagship, genomic-based clinical trial and continues to publish on developments at the vanguard of oncology.

Dr. Adler holds M.D University of Pennsylvania and B.A. from Yale University, summa cum laude.

Michael Russell, MBA - CFO (Consultant)

Michael Russell brings to Biological Dynamics over 30 years of experience in the technology and finance. He has been associated with both private and public companies leading accounting, credit and collections, treasury, financial planning and budgeting, information systems, SOX compliance, and HR functions.

Michael Russell currently serves as VP of Finance & Administration at Enevate. He has held CFO roles at various companies including MaxLinear, American Technology, Cerwin-Vega, and Metallic Power and has held VP positions at Fair Isaac Corporation (FICO), and Vitesse Semiconductor.

He holds an MBA from the UCLA Anderson School of Management and BS in Electrical Engineering from UC Los Angeles.