Application Publications


Bibliography

  1. Hinestrosa, J. P., Dhani, H., Lewis, J.M., Schroeder, G., Balcer, H. I.,  Keith, D., Sheppard, B., Sears, R., Kurzrock, R., & Billings, P.R. Development of a Blood-Based EV Classifier for Detection of Early-Stage Pancreatic Ductal Adenocarcinoma. Communications Medicine 2023; 3:146.

  2. Luna, R., Heineck, D., Hinestrosa, J. P., Dobrovolskia, I., Hamilton, S., Malakian, A., Gustafson, K. T., Huynh, K. T., Kim, S., Ware, J., Stimson, E., Ibsen, C. S., & Ibsen, S. D. Enhancement of Dielectrophoresis-Based Particle Collection from High Conducting Fluids Due to Partial Electrode Insulation. Electrophoresis 2023; Online ahead of print.

  3. Dhani, H., Hinestrosa, J. P., Izaguirre-Carbonell, J., Balcer, H. I., Kurzrock, R., & Billings, P. R. Case Report: Early detection of pancreatic pre-cancer lesion in multimodal approach with exosome liquid biopsy. Frontiers in Oncology 2023; 13:1170513.

  4. Hamilton, S., Shea, D., Ibsen, S., & Brasino, M. On-chip dielectrophoretic recovery and detection of a lactate sensing probiotic from model human saliva. Electrophoresis 2023; 44(3-4):442–449.

  5. Gustafson, K. T., Sayar, Z., Le, H., Gustafson, S. L., Gower, A., Modestino, A., Ibsen, S., Heller, M. J., Esener, S., & Eksi, S. E. cyc-DEP: Cyclic immunofluorescence profiling of particles collected using dielectrophoresis. Electrophoresis 2022; 43(16-17):1784–1798.

  6. Luna, R., Heineck, D. P., Bucher, E., Heiser, L., & Ibsen, S. D. Theoretical and experimental analysis of negative dielectrophoresis-induced particle trajectories. Electrophoresis 2022; 43(12):1366–1377.

  7. Hinestrosa, J. P., Kurzrock, R., Lewis, J. M., Schork, N. J., Schroeder, G., Kamat, A. M., Lowy, A. M., Eskander, R. N., Perrera, O., Searson, D., Rastegar, K., Hughes, J. R., Ortiz, V., Clark, I., Balcer, H. I., Arakelyan, L., Turner, R., Billings, P. R., Adler, M. J., Lippman, S. M., … Krishnan, R. Early-stage multi-cancer detection using an extracellular vesicle protein-based blood test. Communications Medicine 2022; 2:29.

  8. Gustafson, K. T., Huynh, K. T., Heineck, D., Bueno, J., Modestino, A., Kim, S., Gower, A., Armstrong, R., Schutt, C. E., & Ibsen, S. D. Automated fluorescence quantification of extracellular vesicles collected from blood plasma using dielectrophoresis. Lab on a Chip 2021; 21(7):1318–1332.

  9. Hinestrosa, J. P., Searson, D. J., Lewis, J. M., Kinana, A., Perrera, O., Dobrovolskaia, I., Tran, K., Turner, R., Balcer, H. I., Clark, I., Bodkin, D., Hoon, D. S. B., & Krishnan, R. Simultaneous Isolation of Circulating Nucleic Acids and EV-Associated Protein Biomarkers From Unprocessed Plasma Using an AC Electrokinetics-Based Platform. Frontiers in Bioengineering and Biotechnology 2020; 8:581157.

  10. Lewis, J. M., Dhawan, S., Obirieze, A. C., Sarno, B., Akers, J., Heller, M. J., & Chen, C. C. Plasma Biomarker for Post-concussive Syndrome: A Pilot Study Using an Alternating Current Electro-Kinetic Platform. Frontiers in Neurology 2020; 11:685.

  11. Lewis, J., Alattar, A. A., Akers, J., Carter, B. S., Heller, M., & Chen, C. C. A Pilot Proof-Of-Principle Analysis Demonstrating Dielectrophoresis (DEP) as a Glioblastoma Biomarker Platform. Scientific Reports 2019; 9(1):10279.

  12. Turner, R., Madsen, J., Herrera, P. D. S., Wallace, J., Madrigal, J., Hinestrosa, J. P., Dobrovolskaia, I., & Krishnan, R. Cancer Detection at your Fingertips: Smartphone-Enabled DNA Testing. Annual International Conference of the IEEE Engineering in Medicine and Biology Society 2018; 5418–5421.

  13. Lewis, J. M., Vyas, A. D., Qiu, Y., Messer, K. S., White, R., & Heller, M. J. Integrated Analysis of Exosomal Protein Biomarkers on Alternating Current Electrokinetic Chips Enables Rapid Detection of Pancreatic Cancer in Patient Blood. ACS Nano 2018; 12(4):3311–3320.

  14. Ibsen, S. D., Wright, J., Lewis, J. M., Kim, S., Ko, S. Y., Ong, J., Manouchehri, S., Vyas, A., Akers, J., Chen, C. C., Carter, B. S., Esener, S. C., & Heller, M. J. Rapid Isolation and Detection of Exosomes and Associated Biomarkers from Plasma. ACS Nano 2017; 11(7):6641–6651.

  15. Manouchehri, S., Ibsen, S., Wright, J., Rassenti, L., Ghia, E. M., Widhopf, G. F., 2nd, Kipps, T. J., & Heller, M. J. Dielectrophoretic recovery of DNA from plasma for the identification of chronic lymphocytic leukemia point mutations. International Journal of Hematologic Oncology 2016; 5(1):27–35.

  16. Ibsen, S., Sonnenberg, A., Schutt, C., Mukthavaram, R., Yeh, Y., Ortac, I., Manouchehri, S., Kesari, S., Esener, S., & Heller, M. J. Recovery of Drug Delivery Nanoparticles from Human Plasma Using an Electrokinetic Platform Technology. Small 2015; 11(38):5088–5096.

  17. Lewis, J. M., Heineck, D. P., & Heller, M. J. Detecting cancer biomarkers in blood: challenges for new molecular diagnostic and point-of-care tests using cell-free nucleic acids. Expert Review of Molecular Diagnostics 2015, 15(9):1187–1200.

  18. Sonnenberg, A., Marciniak, J. Y., Skowronski, E. A., Manouchehri, S., Rassenti, L., Ghia, E. M., Widhopf, G. F., 2nd, Kipps, T. J., & Heller, M. J. Dielectrophoretic isolation and detection of cancer-related circulating cell-free DNA biomarkers from blood and plasma. Electrophoresis 2014; 35(12-13):1828–1836.

  19. Sonnenberg, A., Marciniak, J. Y., Rassenti, L., Ghia, E. M., Skowronski, E. A., Manouchehri, S., McCanna, J., Widhopf, G. F., 2nd, Kipps, T. J., & Heller, M. J. Rapid electrokinetic isolation of cancer-related circulating cell-free DNA directly from blood. Clinical Chemistry 2014, 60(3):500–509.