PRESENTATION: Monday, May 16, 2022
7:00 AM. – 9:00 AM CST
PODIUM PD53-07, Room 255/Abstract ID: 22-7466
TITLE: Bladder Cancer – Basic Research & Pathophysiology III

Jean M. Lewis, Ph.D., Associate Director, Research, Biological Dynamics to present the company’s latest bladder cancer data.

PRESENTATION ABSTRACT
Detection of Early-stage Bladder Cancer Using Plasma Extracellular Vesicle Protein Biomarkers
There is a need for earlier bladder cancer screening to reduce lifetime costs and improve patient outcomes. Urinary protein biomarkers have shown some promise, but reported sensitivities appear compromised by low and/or variable biomarker concentrations. In this study, we investigated the potential of using extracellular vesicles (EV) circulating in the blood to detect stage I and II bladder cancer. Using an alternating current electrokinetic (ACE) platform to purify EVs from plasma, we show how a multi-marker EV protein-based methodology can be used to discriminate bladder cancer cases from controls in stage I and II cases.

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