EVENT: Tuesday, March 1, 2022, 08:00 Central European Time (CET) – Wednesday, March 2, 2022, 18:00 (CET)

PRESENTATION: Wednesday, March 2
11:00 AM CET/5:00 AM EST

Dr. Jean M. Lewis, Associate Director of Research at Biological Dynamics, Inc., will discuss her team’s work developing exosome-based liquid biopsy assays using the company’s proprietary platform. The presentation, Multi-Cancer Early Detection Based on a Classifier for Extracellular Vesicle Biomarkers, illustrates the potential utility of EV-protein biomarkers in the non-invasive diagnosis of cancer applications. Recently, her research has been directed towards identifying EV biomarkers for early-stage cancer liquid biopsy.

Presentation Abstract
Simultaneous detection of multiple, early-stage cancers was tested using extracellular vesicle (EV) bound protein markers from plasma purified by an alternating current electrokinetic (ACE) microarray. In a case-control study, this method detected 95.7% of pancreatic, 75.0% of ovarian, and 43.8% of bladder cancers at 99.5% specificity, all at stages I and II. The initial results suggest that this liquid biopsy screen may have great promise for early-stage, multi-cancer screening.

Session Title: Technology Developments in the Circulating Biomarkers Space

SelectBio Circulating Biomarkers Europe brings together academics and industry participants from around the world focused on research, biomarker analyses and therapeutics development leveraging the cargo from Exosomes and Extracellular Vesicles (EVs). An important component of this conference is to focus upon the development of Liquid Biopsies using circulating cell-free DNA (cfDNA), circulating tumor cells (CTCs) and other biomarkers found in biofluids.

Additionally, the conference focuses on the Therapeutic and Drug Delivery Opportunities Enabled by Extracellular Vesicles (EVs). In this vein, key opinion leaders in this space will be presenting at this conference.

Presentations, Panel Discussions and Round-Table Workshops from key opinion leaders in the field form the basis of this conference.